The Endoscopic Assesment of Intestinal Grafts

Purpose

The study validates prospectively a new endoscopic scoring system (Gothenburg Intestinal Transplant Endoscopy Score, GITES) designed to summarize and stratify the abnormal ileal endoscopic findings after intestinal transplantation. GITES is a five-tier, four grade score which asseses mucosal friability, mucosal erythema and mucosal injury (ulcerations) as well as villous changes according to severity. These features (i.e., endoscopic descriptors) are also grouped from mild to very severe in the same sequence as observed during the progression of several pathologic conditions encountered after intestinal transplantation (acute rejection, infectious enteritis).

Conditions

  • Transplant; Intestine
  • Transplant; Complication, Rejection
  • Transplant; Failure, Bowel
  • Enteritis
  • Mucosal Inflammation

Eligibility

Eligible Ages
All ages
Eligible Genders
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • transplantation of a segment of small intestine (as isolated graft or together with other organs)

Exclusion Criteria

  • contraindications for ileoscopy

Study Design

Phase
Study Type
Observational
Observational Model
Cohort
Time Perspective
Prospective

Recruiting Locations

MedStar Georgetown University Hospital
Washington, District of Columbia 20007
Contact:
Stuart Kaufman, MD

More Details

Status
Unknown status
Sponsor
Sahlgrenska University Hospital, Sweden

Study Contact

Mihai Oltean, M.D., Ph.D.
00 46 31 342 1000
mihai.oltean@surgery.gu.se