Children With Diabetes at Risk for Heart Disease.
Purpose
Patients with type 1 diabetes type 1 (DM1) have increased risk of death due to heart disease and stroke. These cardiovascular conditions (CVD) are the leading cause of death in patients with DM1 younger than 40 years of age and up to 35% of all persons with DM1 will die before age 55 from CVD. Strategies are needed to help identify adolescents with DM1 at risk for CVD so that interventions to prevent heart disease and stroke can be undertaken.
Conditions
- Diabetes Mellitus, Type 1
- Diabetes Complications
Eligibility
- Eligible Ages
- Between 12 Years and 21 Years
- Eligible Genders
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
Diabetes type 1 or Healthy
Exclusion Criteria
Taking medications that lower cholesterol Duration of type 1 diabetes < 1 year.
Study Design
- Phase
- Study Type
- Observational
- Observational Model
- Case-Control
- Time Perspective
- Cross-Sectional
Arm Groups
| Arm | Description | Assigned Intervention |
|---|---|---|
| Diabetes | Children with diabetes type 1 , 12-21 years old | |
| Healthy | Healthy children 12-21 years old |
Recruiting Locations
Washington, District of Columbia 20007
Stephanie Gubb
202-444-1210
More Details
- Status
- Unknown status
- Sponsor
- Georgetown University
Study Contact
Evgenia Gourgari, MD2024441210
Detailed Description
Patients with type 1 diabetes and healthy controls will have evaluation of their lipid profile. Arterial stiffness, heart rate variability and adiposity measurements will be done in patients with type 1 diabetes and healthy controls. Blood pressure and heart rate will be recorded. 50 ml of urine will be collected from patients and controls. All studies will be performed as a single outpatient visit at Georgetown University.