CLUSTER Trial for Outbreak Detection and Response
Purpose
Despite the critical importance of identifying hospital-associated outbreaks as early as possible in order to limit their spread, there are currently no standardized methods for cluster detection. The CLUSTER Trial (Cluster Linkage Using Statistics to Trigger and Evaluate Response) will assess whether a statistically-based automated cluster detection method coupled with a robust response protocol will enable rapid containment of hospital clusters as measured by a reduction in cluster size and duration as compared to routine hospital cluster detection methods coupled with the same response protocol. Note: that enrolled "subjects" represents 82 individual HCA Healthcare hospitals that have been randomized
Condition
- Cluster Detection
Eligibility
- Eligible Ages
- All ages
- Eligible Genders
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- All U.S. HCA Healthcare hospitals that provide inpatient care. - Facilities that are reporting to the centralized data warehouse during the study period. Facility
Exclusion Criteria
- Note: unit of randomization is the hospital.
Study Design
- Phase
- N/A
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel Assignment
- Intervention Model Description
- Cluster randomized controlled trial
- Primary Purpose
- Prevention
- Masking
- None (Open Label)
Arm Groups
| Arm | Description | Assigned Intervention |
|---|---|---|
|
Active Comparator Routine cluster detection |
Hospitals will use routine practices for cluster detection with a structured cluster response protocol when a cluster is detected. |
|
|
Active Comparator Enhanced cluster detection |
Hospitals will use an automated statistical cluster detection tool in addition to routine practices for cluster detection with a structured cluster response protocol when a cluster is detected. |
|
More Details
- Status
- Active, not recruiting
- Sponsor
- Harvard Pilgrim Health Care