Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors
Purpose
This phase III trial evaluates whether a web-based intervention called Current Together after Cancer (CTAC) works to increase the number of patients with surgically removed (resected) colorectal cancer who receive surveillance care that aligns with current guidelines (guideline-concordant). Surveillance care after resection of colorectal cancer is critical to detect potentially curable return of disease (recurrence), yet up to 60% of colorectal cancer survivors fail to receive surveillance. This may be due to a lack of knowledge about the purpose of surveillance care and the risks of cancer recurrence, or a lack of confidence for managing surveillance care. The CTAC intervention is an online education intervention designed to improve patients' knowledge about surveillance and their self-efficacy for managing surveillance, and to promote effective communication with supporters and supporter engagement in patients' surveillance in a way that is aligned with each patient's preferences. By increasing a patient's knowledge, self-efficacy, and satisfaction with their supporter's engagement in their care, the CTAC intervention may increase the number of patients who receive guideline-concordant surveillance care after resection of colorectal cancer.
Conditions
- Colorectal Cancer Stage II
- Colorectal Cancer Stage III
Eligibility
- Eligible Ages
- Over 18 Years
- Eligible Sex
- All
- Accepts Healthy Volunteers
- Yes
Criteria
Inclusion Criteria:
- PATIENTS:
- Patient participants must have newly diagnosed surgically resected, stage II or
stage III colorectal cancer per the timing described below
- Patient participants must have an adult in their life who supports them in their
colorectal cancer journey who they might be willing to invite to join them in
viewing an educational website. This is determined via the question: "Do you have an
adult in your life, such as a spouse/partner, family member or friend, who supports
you with your colorectal cancer journey and may be willing to view a website with
you? When we say, "supports you in your colorectal cancer journey", we mean things
like, helping you keep and get to medical appointments, talking with you and/or your
doctors about your cancer, or helping you make decisions about your cancer."
- Those who respond "no" to the question above will be told that "Because this
study is for patients and a supporter to view the website together, you are not
eligible for this study, but there may be other studies you are eligible for in
the future".
- NOTE: The above question will be used to define "supporter" for purposes of
this study. Examples of supporters include a spouse, partner, sibling, adult
child, another family member, or friend.
- NOTE: The supporter does not have to agree to participate in the study in order
for the patient to be eligible for this study. Justification for requiring the
enrolled patient to have a supporter (whether the supporter is invited or
participates) is based on the study's underlying conceptual framework
- Patient participants must not have recurrent or metastatic (stage IV) colorectal
cancer
- Patient participants must not have a prior or concurrent malignancy whose natural
history or treatment (in the opinion of the treating physician) has the potential to
interfere with the efficacy assessment of this intervention
- Patient participants must be registered within 90 - 180 days of surgical resection
- Patient participants must be ≥ 18 years of age at the time of
registration/randomization. The lower cutoff of 18 was determined because the lower
age range of patients that may be recruited to Southwest Oncology Group (SWOG)
studies is 18
- Patient participants must have Zubrod performance status of 0-2
- Patient participants must be able to read English or Spanish since the website for
the intervention and control arm are available in English and Spanish
- Patient participants must: 1) be able to complete Patient Reported Outcome (PRO)
questionnaires in English or Spanish, and 2) agree to complete PROs at all scheduled
timepoints
- Patient participants will be encouraged to provide an email address or cell phone
number, if possible, for the purpose of being contacted by staff at the University
of Michigan who will provide access to the educational website. For those who do not
wish to provide or create an email address or a cell phone number, they may still
participate with alternate methods
- Patient participants must not be enrolled or be planning to enroll in a clinical
trial of investigational treatment that includes imaging and/or laboratory
monitoring for the duration of this trial
- NOTE: Patient participants are allowed to be co-enrolled on other non-treatment
clinical trials
- SUPPORTER PARTICIPANT:
- Supporter participants must be ≥ 18 years of age at the time of
registration/randomization
- Supporter participants must be able to read English or Spanish since the educational
website is available in English and Spanish
- Supporter participants must have been identified by the patient as a person who may
be willing to join them in reviewing the educational website
- PATIENT AND SUPPORTER:
- NOTE: As a part of the Oncology Patient Enrollment Network (OPEN) registration
process the treating institution's identity is provided in order to ensure that the
current (within 365 days) date of institutional review board approval for this study
has been entered in the system
- Patient and supporter participants must be informed of the investigational
nature of this study and must sign and give informed consent in accordance with
institutional and federal guidelines. This protocol does not permit use of
Legally Authorized Representative
Study Design
- Phase
- Phase 3
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel Assignment
- Primary Purpose
- Health Services Research
- Masking
- None (Open Label)
Arm Groups
| Arm | Description | Assigned Intervention |
|---|---|---|
|
Experimental Group 1 (CTAC) |
Patients and supporter participants receive access to the CTAC intervention website and may review the content as frequently as they like for up to 16 months on study. |
|
|
Active Comparator Group 2 (Control) |
Patients and supporter participants receive access to a general health education website and may review the content as frequently as they like for up to 16 months on study. |
|
Recruiting Locations
Georgetown, South Carolina 29440
More Details
- Status
- Recruiting
- Sponsor
- SWOG Cancer Research Network
Study Contact
Detailed Description
PRIMARY OBJECTIVE: I. To evaluate whether the patients randomized to the Current Together After Cancer (CTAC) intervention website compared to the CTAC control website have higher rates of guideline-concordant colorectal cancer (CRC) surveillance at 12 months after registration. SECONDARY OBJECTIVES: I. To assess patient reported knowledge about surveillance at 3 and 16 months post-patient registration. (Comparing CTAC intervention versus [vs.] control) II. To assess patient reported self-efficacy in management of surveillance 3 and 16 months post-patient registration using previously developed CRC screening self-efficacy measure. (Comparing CTAC intervention vs. control) III. To assess patient reported satisfaction with supporter engagement in surveillance 3 and 16 months post-patient registration. (Comparing CTAC intervention vs. control) EXPLORATORY OBJECTIVES: I. To assess the implementation of CTAC into clinic workflow, and to better understand barriers and facilitators to the delivery of the intervention arm using a mixed-methods approach. (For the process evaluation of the CTAC intervention) II. To explore the association between supporter participation in the assigned CTAC intervention at 3 months with receipt of CRC surveillance at 16 months. (Regarding supporter participation) III. To explore the association between supporter participation in the assigned CTAC intervention at 3 months with knowledge about surveillance; at 16 months. (Regarding supporter participation) IV. To explore the association of supporter participation in the assigned CTAC intervention at 3 months with self-efficacy in management of surveillance at 16 months. (Regarding supporter participation) V. To explore the association of supporter participation in the assigned CTAC intervention at 3 months. (Regarding supporter participation) OUTLINE: Patients are randomized to 1 of 2 groups and supporter participants are assigned to the arm to which their patient was randomized. GROUP 1: Patients and supporter participants receive access to the CTAC intervention website and may review the content as frequently as they like for up to 16 months on study. GROUP 2: Patients and supporter participants receive access to a general health education website and may review the content as frequently as they like for up to 16 months on study.